VILLUS

plural Villi, in anatomy, any of the small, slender, vascular projections that increase the surface area of a membrane. Important villous membranes include the sac that encloses unborn (fetal) mammals and the mucous-membrane coating of the small intestine. In humans the villi project into the intestinal cavity, greatly increasing the area for food absorption and adding digestive secretions. The villi number about 6,000 to 25,000 per square inch (10 to 40 per square millimetre) of tissue. They are most prevalent at the beginning of the small intestine and diminish in number toward the end of the tract. The large number of villi give the internal intestinal wall a velvety appearance. Each villus has a central core composed of one artery and one vein, a strand of muscle, a centrally located lymphatic capillary (lacteal), and connective tissue that adds support to the structures. The blood vessels are thought to transport proteins and carbohydrates absorbed by the villi's cells, while the lymphatic capillary removes droplets of emulsified fat (chyle). The muscle strand allows the villi to contract and expand; it is believed that these contractions empty the contents of the lacteal into larger lymphatic vessels. Covering the core of a villus is the surface mucous-membrane layer. This is mainly composed of two cell types: tall, narrow, columnar cells that absorb the substances passed into the blood and lymphatic vessels; and goblet cells, rounded at the end, that secrete mucus into the intestinal cavity. On the surface of each columnar cell there are about 600 very fine projections called microvilli that further increase the absorptive area of each villus. Villi of the intestine move in swaying, contracting motions. These movements are believed to increase the flow of blood and lymph and to enhance absorption. The villi of the small intestine absorb about 2 gallons (7 1/2 litres) of fluid per day, and absorption seems to be indiscriminate.