I. Maine /meɪn/ BrE AmE written abbreviation , ME
a state in the northeast of the US, next to the Atlantic coast and the border with Canada. Maine is the largest state in ↑ New England , and is known for its beautiful forests, mountains, and coast.
II. ME /ˌem ˈiː/ BrE AmE noun
1 . [uncountable] British English (myalgic encephalomyelitis) an illness that makes you feel very tired and weak and can last for a long time:
ME sufferers
2 . [countable] American English the abbreviation of medical examiner