vi ‧ cis ‧ si ‧ tudes /vəˈsɪsətjuːdz, vɪˈsɪsətjuːdz $ -tuːdz/ BrE AmE noun [plural] formal
[ Date: 1500-1600 ; Language: Latin ; Origin: vicissitudo , from vicissim 'in turn' , from vicis ; ⇨ ↑ vicarious ]
the continuous changes and problems that affect a situation or someone’s life
vicissitudes of
the vicissitudes of married life