[puff.er] n (1629) 1: one that puffs
2. a: any of a family (Tetraodontidae) of chiefly tropical marine bony fishes which can distend themselves to a globular form and most of which are highly poisonous--called also blowfish, globefish b: any of various fish of the same order (Tetraodontiformes syn. Plectognathi) as the puffers