I. ˈa-nə-ˌdīn adjective
Etymology: Latin anodynos, from Greek anōdynos, from a- + odynē pain; probably akin to Old English etan to eat
Date: 1543
1. : serving to alleviate pain
2. : not likely to offend or arouse tensions : innocuous
II. noun
Date: circa 1550
1. : something that soothes, calms, or comforts
the anodyne of bridge, a comfortable book, or sport — Harrison Smith
2. : a drug that allays pain