Synonyms and related words :
adverse circumstances, adversity, affliction, aggravation, annoyance, blight, bummer, calvary, care, cross, crucible, curse, difficulties, difficulty, downer, fiery ordeal, hard knocks, hard life, hard lot, hardcase, hardship, irritation, oppression, ordeal, persecution, plight, predicament, pressure, rigor, sea of troubles, stress, stress of life, trial, trials and tribulations, trouble, troubles, vale of tears, vicissitude, visitation