Synonyms and related words :
bear hard upon, bear on, bear upon, beat down, burden, burthen, cast down, charge, crush one, cumber, damp, dampen, dampen the spirits, darken, dash, deject, depress, discourage, dishearten, dispirit, encumber, exhaust, freight, go hard with, go ill with, hamper, handicap, haunt, haunt the memory, knock down, lade, lie on, load, lower, lower the spirits, obsess, oppress, overburden, overload, overtax, overweight, press, press down, press hard upon, prey on, rest hard upon, rest on, sadden, saddle, sink, tax, tire, try one, wear out, wear upon one, weary, weigh down, weigh heavy on, weigh heavy upon, weigh on, weight down