I .
1.
to start being independent :
I knew it was time I struck out on my own.
2.
( NAmE , informal ) to fail or be unsuccessful :
The movie struck out and didn't win a single Oscar.
II .
strike out | ˌstrike sb ↔ ˈout
( in baseball ) to fail to hit the ball three times and therefore not be allowed to continue hitting; to make sb do this
—related noun strikeout