adj excited; heightened.
2. irritate ·vt to render null and void.
3. irritate ·vt to produce irritation in; to stimulate; to cause to contract. ·see irritation, ·noun, 2.
4. irritate ·vt to increase the action or violence of; to heighten excitement in; to intensify; to stimulate.
5. irritate ·noun to make morbidly excitable, or oversensitive; to fret; as, the skin is irritated by friction; to irritate a wound by a coarse bandage.
6. irritate ·vt to excite anger or displeasure in; to provoke; to tease; to exasperate; to annoy; to vex; as, the insolence of a tyrant irritates his subjects.