If something moves ~, it moves in the opposite direction to the wind. If something is ~, the wind is blowing away from it.
...riding a bike ~...
The rich went to live in the west of London, ~ of the smell of people and industry.
? downwind
ADV: ADV after v, be ADV, oft ADV of n
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Upwind is also an adjective.
...big trees at the forest’s ~ edge.
ADJ: ADJ n