PYTHONESS Meaning of PYTHONESS in English n. 1 the Pythian priestess. 2 a witch. [ ME f. OF phitonise f. med.L phitonissa f. LL pythonissa fem. of pytho f. Gk puthon soothsaying demon: cf. PYTHON ] Concise Oxford English dictionary. Краткий оксфордский словарь английского языка. 2012