n. 25B6; noun
he clenched his fists in frustration : EXASPERATION, annoyance, anger, vexation, irritation; disappointment, dissatisfaction, discontentment, discontent; informal aggravation.
the frustration of his attempts to introduce changes : THWARTING, defeat, prevention, foiling, blocking, spoiling, circumvention, forestalling, disappointment, derailment; obstruction, hampering, hindering; failure, collapse.