v. 25B6; verb
what maddens people most is his vagueness : INFURIATE, exasperate, irritate; incense, anger, enrage, provoke, upset, agitate, vex, irk, make someone's hackles rise, make someone see red; informal aggravate, make someone's blood boil, make livid, get up someone's nose, get someone's goat, get someone's back up; Brit. informal nark; N. Amer. informal tee off, tick off.
they were maddened with pain : DRIVE MAD, drive insane, derange, unhinge, unbalance; informal drive round the bend.