BUFFO Meaning of BUFFO in English [ 'bʊfəʊ ]■ noun ( plural ~s ) a comic part or actor in Italian opera. ■ adjective of or typical of Italian comic opera.OriginC18: Ital., 'puff of wind, ~on'. Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004