CAYENNE Meaning of CAYENNE in English [ keɪ'ɛn ](also ~ pepper ) ■ noun a pungent, hot-tasting red powder prepared from dried chillies.OriginC18: from Tupi kyynha , quiynha , later assoc. with Cayenne in French Guiana. Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004