EMPYEMA Meaning of EMPYEMA in English [ ˌɛmpʌɪ'i:mə ]■ noun Medicine the collection of pus in a body cavity, especially in the pleural cavity.OriginME: via late L. from Gk empuēma , from empuein 'suppurate'. Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004