MACROCEPHALIC Meaning of MACROCEPHALIC in English [ ˌmakrə(ʊ)sɪ'falɪk , -kɛ'falɪk- ](also macrocephalous ) ■ adjective Anatomy having an unusually large head.Derivativesmacrocephaly noun Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004