MACROCYCLIC Meaning of MACROCYCLIC in English [ ˌmakrə(ʊ)'sʌɪklɪk , -'sɪk- ]■ adjective Chemistry relating to or denoting a ring composed of a relatively large number of atoms.Derivativesmacrocycle noun Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004