MALADY Meaning of MALADY in English ■ noun ( plural maladies ) literary a disease or ailment.OriginME: from OFr. maladie , from malade 'sick', based on L. male 'ill' + habitus 'having (as a condition)'. Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004