MELANOMA Meaning of MELANOMA in English [ ˌmɛlə'nəʊmə ]■ noun Medicine a tumour of melanin-forming cells, especially a malignant tumour associated with skin cancer.OriginC19: from Gk melas, melan- 'black' + -oma . Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004