NYSTATIN Meaning of NYSTATIN in English [ 'nʌɪstətɪn , 'nɪs- ]■ noun an antibiotic used chiefly to treat fungal infections.Origin1950s: from N(ew) Y(ork) Stat(e) (where it was developed) + -in 1 . Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004