SERPIGINOUS Meaning of SERPIGINOUS in English [ sə:'pɪdʒɪnəs ]■ adjective Medicine (of a skin lesion or ulcerated region) having a wavy margin.OriginME: from med. L. serpigo , serpigin- 'ringworm' + -ous . Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004