VADE MECUM Meaning of VADE MECUM in English [ ˌvα:di'meɪkəm , ˌveɪdi , 'mi:kəm ]■ noun a handbook or guide kept constantly at hand.OriginC17: mod. L., lit. 'go with me'. Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004