GIST Meaning of GIST in English transcription, транскрипция: [ dʒɪst ]n. 1 the substance or essence of a matter. 2 Law the real ground of an action etc. [OF, 3rd sing. pres. of gesir lie f. L jacere] English main colloquial, spoken dictionary. Английский основной разговорный словарь. 2012