noun
COLLOCATIONS FROM CORPUS
■ ADJECTIVE
enhanced
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This has led to difficulties in interpretation of the possible sequence of events in the development of enhanced platelet reactivity in diabetics.
■ NOUN
aggregate
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The above studies have attempted to assess the presence of circulating platelet aggregates .
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Along with this there was a significant reduction in circulating platelet aggregates .
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Other authors found similar findings with regard to circulating platelet aggregates .
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Formalin fixes platelet aggregates which would be removed during the centrifugation to produce platelet-rich plasma.
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Therefore the platelet-aggregate ratio would be low in the presence of circulating platelet aggregates .
aggregation
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Thus diminution of prostacyclin production and stimulation of platelet aggregation both mediated by lipid peroxides could contribute to thrombosis on atheromatous plaques.
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Biological activity of platelet activating factor was measured by platelet aggregation using a Chrono-log Corporation aggregometer.
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The L-arginine-NO system exerts various biological actions including vascular smooth muscle relaxation and inhibition of platelet aggregation .
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A positive correlation was found between glycosylated haemoglobin concentration and the prostacyclin concentration necessary to inhibit ADP-induced platelet aggregation by 50 percent.
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Spontaneous platelet aggregation Several studies have attempted to assess whether there is evidence of increased circulating platelet aggregates in diabetic subjects.
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Platelets were resuspended in washing buffer at appropriate concentrations for platelet aggregation measurement.
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However, this suggestion depends on the assumption that prostacyclin is continually produced by arterial wall to prevent platelet aggregation .
blood
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Other cell types - leucocytes and blood platelets - spend much of their time circulating freely and thus showing no adhesive interactions.
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It can also be readily extracted from out-of-date human blood platelets .
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Prostacyclin has powerful metabolic effects on blood platelets .
count
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Correlation with platelet count was particularly good in colonic disease.
function
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For instance, there is no absolutely satisfactory test of platelet function .
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This would enable prospective studies to be performed to determine the importance of platelet function in the development of vascular disease.
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Studies in this field are difficult to interpret due to the inherent variability of the measurements of platelet function .
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The mechanism of lipid-induced effects of platelet function has received considerable attention.
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In addition to problems intrinsic to the methodology of platelet function , problems also arise from the diabetic groups studied.
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For these reasons studies detailing the effects of diabetic control on platelet function must be interpreted with caution.
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Gliclazide is the sulphonylurea that has received most study in terms of possible effects on platelet function .
■ VERB
show
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These authors have shown that colonic platelet activating factor content was significantly increased irrespective of colonic inflammation.
suggest
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Therefore we suggest that platelet activating factor should be considered as a global mucosal activity marker.
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These results suggest the involvement of platelet activating factor in the endothelin induced fibrinolytic activation and subsequently developed mucosal haemorrhagic lesion.
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This suggests that platelets must possess very sophisticated intracellular control mechanisms.
EXAMPLES FROM CORPUS
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A minor fraction of phosphatidylserine may be present at the outer surface of platelets, but this can not usually be detected.
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An ion exchange process creates an aqueous slurry of platelets of molecular dimensions.
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Maternity blues linked to platelet receptors TWO-THIRDS of women suffer from postnatal depression, accompanied by crying, confusion and tension.
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The distributional asymmetries of phospholipids in the plasma membrane of erythrocytes and platelets are shown in Fig. 2.
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The earliest finding is the platelet adhesion to collagen fibres followed by aggregation and formation of a platelet plug.
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The L-arginine-NO system exerts various biological actions including vascular smooth muscle relaxation and inhibition of platelet aggregation.
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These findings suggest that lipoprotein abnormalities in the diabetic state may also indirectly affect platelet function by damaging vascular endothelium.
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This would enable prospective studies to be performed to determine the importance of platelet function in the development of vascular disease.