NOPE Meaning of NOPE in English nope S3 /nəʊp $ noʊp/ BrE AmE adverb spoken informal [ Date: 1800-1900 ; Origin: no ] used to say ‘no’ when you answer someone:‘Hungry?’ ‘Nope, I just ate.’ Longman Dictionary of Contemporary English. Longman - Словарь современного английского языка. 2012