to have an effect on sb/sth :
I hope nothing (= nothing unpleasant) has happened to them.
It's the best thing that has ever happened to me.
What's happened to your car?
Do you know what happened to Gill Lovecy (= have you any news about her) ?
to have an effect on sb/sth :
I hope nothing (= nothing unpleasant) has happened to them.
It's the best thing that has ever happened to me.
What's happened to your car?
Do you know what happened to Gill Lovecy (= have you any news about her) ?
Oxford Advanced Learner's English Dictionary. Оксфордский английский словарь для изучающик язык на продвинутом уровне. 2005