adjective
1.
( of a building or place ) in very bad condition; that has not been taken care of
SYN neglected :
run-down inner-city areas
2.
( of a business, etc. ) not as busy or as active as it used to be :
run-down transport services
3.
[ not before noun ] ( of a person ) tired or slightly ill / sick, especially from working hard :
to be run-down