adj. 1 Sometimes, regardless of. despite, notwithstanding; in spite of, heedless of, Non-Standard irregardless Regardless of her father's protestations, she continued to go out with William
adv. 2 notwithstanding, nevertheless, no matter what, in any event, in any case, at all events, anyway, anyhow, Non-Standard irregardless She heard his threats but is going out with William regardless