MEPHISTOPHELES Meaning of MEPHISTOPHELES in English n.1 an evil spirit to whom Faust, in the German legend, sold his soul. 2 a fiendish person. Derivatives: Mephistophelean adj. Mephistophelian adj. Etymology: G (16th c.), of unkn. orig. Oxford English vocab. Оксфордский английский словарь. 2012