REFRIGERANT Meaning of REFRIGERANT in English n. & adj. --n. 1. a substance used for refrigeration. 2 Med. a substance that cools or allays fever. --adj. cooling. Etymology: F r{eacute}frig{eacute}rant or L refrigerant- (as REFRIGERATE) Oxford English vocab. Оксфордский английский словарь. 2012