a.
1.
Unfortunate, unlucky, infelicitous.
2.
Wretched, miserable, distressed, afflicted, sorrowful, heart-sick.
3.
Grievous, disastrous, calamitous, severe, trying, painful, unfortunate, unlucky, sad, afflicting, afflictive, distressing, deplorable, dire.
4.
Unpropitious, unlucky, malign, inauspicious, sinister, evil.