noun the state or quality of being irritable; quick excitability; petulance; fretfulness; as, irritability of temper.
2. irritability ·noun a condition of morbid excitability of an organ or part of the body; undue susceptibility to the influence of stimuli. ·see irritation, ·noun, 3.
3. irritability ·noun a natural susceptibility, characteristic of all living organisms, tissues, and cells, to the influence of certain stimuli, response being manifested in a variety of ways, as that quality in plants by which they exhibit motion under suitable stimulation; ·esp., the property which living muscle processes, of responding either to a direct stimulus of its substance, or to the stimulating influence of its nerve fibers, the response being indicated by a change of form, or contraction; contractility.