MONOSOMIC Meaning of MONOSOMIC in English I. | ̷ ̷ ̷ ̷|sōmik adjectiveEtymology: mon- + -somic : having one less than the diploid number of chromosomes II. noun( -s ) : a monosomic individual Webster's New International English Dictionary. Новый международный словарь английского языка Webster. 2012