PSYCHO Meaning of PSYCHO in English /suy"koh/ , n. , pl. psychos , adj. Slang.n.1. a psychopathic or neurotic person. adj.2. psychopathic; psychoneurotic. [ 1935-40; shortened form ] Random House Webster's Unabridged English dictionary. Полный английский словарь Вебстер - Random House . 2012