|han(d)ˌshülə(r)ˈkris(h)chən- noun
Usage: usually capitalized H&S&C
Etymology: after Alfred J. Hand b 1868 American physician + Artur Schüller b 1874 Austrian neurologist + Henry Christian b 1876 American physician
: an inflammatory histiocytosis associated with disturbances in cholesterol metabolism that occurs chiefly in young children and is marked by cystic defects of the skull, exophthalmos, and diabetes insipidus