City of Hellenistic Phrygia , near modern Dinar, Turkey.
The city was built by Antiochus I (Antiochus Soter) in the 3rd century BC on the Maeander ( Menderes ) River. Superseding the fortress city of Celaenae, it was placed in a commanding position on the great east-west trade route of the Seleucid dynasty . In the 2nd century BC Apamea passed to the rule of the Roman Republic and Empire and became an important centre for Italian and Jewish traders. Declining after the 3rd century AD, it was captured by Turkish invaders in 1070 and thereafter was destroyed by an earthquake.