METHAMPHETAMINE

also called d-desoxyephedrine, byname speed potent stimulant drug of the amphetamine series, used in medicine as an appetite suppressant in treating obesity and as a stimulant of the central nervous system in treating anesthetic overdose and narcolepsy. Methamphetamine was introduced into medicine in 1944 and is sold under Methedrine and other trade names. Its action is similar to that of amphetamine (q.v.). It may be administered orally or by intravenous injection. The ability of methamphetamine to overcome fatigue and provide increased energy has led to considerable abuse of the drug. Its untoward effects on the body (such as increased heart rate and blood pressure) render it a dangerous drug when misused; and because of the rapid development of tolerance common to the amphetamines (a condition in which the user requires increased doses for a consistent effect), it is unsatisfactory for prolonged use. The euphoria, excitement, and sleeplessness experienced by persons on the drug may give way to severe depression once the dose wears off. The excessive use of methamphetamine can eventually induce a toxic psychosis characterized by paranoid delusions and hallucinations.