RINGER'S SOLUTION

one of the first laboratory solutions of salts in water shown to prolong greatly the survival time of excised tissue; it was introduced by the physiologist Sidney Ringer in 1882 for the frog heart. The solution contains sodium chloride, potassium chloride, calcium chloride, and sodium bicarbonate in the concentrations in which they occur in body fluids. Mammalian Ringer's solution (Locke's, or Ringer-Locke's, solution) differs in that it contains glucose and more sodium chloride than the original solution.