noun
1.
Synonyms: trial 1, calvary, cross, crucible, ordeal, tribulation, visitation
Related Word: mischance, mishap
Contrasted words: alleviation, assuagement, easement, relief
Antonyms: consolation, solace
2.
Synonyms: sorrow , anguish, care, ||dole, grief, heartache, heartbreak, regret, rue, woe
3.
Synonyms: sickness 1, diseasedness, disorder, illness, indisposition, infirmity, unhealth