verb
1.
to disturb and upset nervously
her persistent prying soon annoyed her hostess
Synonyms: abrade, bother, ||bug, chafe, exercise, fret, gall, irk, provoke, ruffle, vex; compare irritate
Related Word: agitate, disturb, perturb, upset
Idioms: get in one's hair
Contrasted words: comfort, console, solace; content, gratify, please, satisfy
Antonyms: soothe
2.
Synonyms: worry 1, bedevil, beleaguer, gnaw, hagride, harass, harry, pester, plague, tease
Related Word: badger, bait, chivy, heckle, hector; chafe, distress, gall, rub
Idioms: get ( or grate) on one's nerves, rub one the wrong way
Contrasted words: disregard, ignore, overlook; appease, calm, dulcify, mollify; cool, lull, subdue