transcription, транскрипция: [ vɪsɪsɪtju:dz, AM -tu:dz ]
You use vicissitudes to refer to changes, especially unpleasant ones, that happen to someone or something at different times in their life or development. ( FORMAL )
Whatever the vicissitudes of her past life, Jill now seems to have come through.
N-PLURAL : oft N of n