MAJOR-DOMO Meaning of MAJOR-DOMO in English [ ˌmeɪdʒə'dəʊməʊ ]■ noun ( plural ~s ) the chief steward of a large household.OriginC16: via Sp. and Ital. from med. L. major domus 'highest official of the household'. Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004