adjective
EXAMPLES FROM CORPUS
▪
Initial therapy of patients with large tumor masses has been complicated by large releases of intracellular potassium with resultant refractory hyperkalemia.
▪
Monamine oxidase inhibitors are used occasionally in migraine patients who are refractory to other prophylactic drugs.
▪
The tale of Gormenghast requires a large number of refractory animals, few of them capable of taking direction.