Variant: also Creutz · feld-Ja · kob disease
Pronunciation: ' kro ̇ its- ˌ felt- ' yä-( ˌ )k ō b-
Function: noun
Etymology: Hans G. Creutzfeldt † 1964 German psychiatrist and Alfons M. Jakob † 1931 German psychiatrist
Date: 1963
: a rare progressive fatal encephalopathy caused by a prion and marked by development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination