CREUTZFELDT-JAKOB DISEASE

[Creutz.feldt-Ja.kob disease] also Creutz.feld-Ja.cob disease n [Hans G. Creutzfeldt d. 1964 Ger. psychiatrist and Alfons M. Jakob d. 1931 Ger. psychiatrist] (1963): a rare progressive fatal encephalopathy caused by a slow virus and marked by development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination