[lo.co] adv or adj [It dial., there, fr. L in loco in the place] (ca. 1801): in the register as written--used as a direction in music
[2]loco n, pl locos or locoes [MexSp, fr. Sp, crazy] (1844) 1: locoweed
2: locoism [3]loco vt (1884) 1: to poison with locoweed
2: to make frenzied or crazy [4]loco adj [Sp] (1887) slang: mentally disordered: crazy, frenzied