SAIN Meaning of SAIN in English [sain] vt [ME, fr. OE segnian, fr. LL signare, fr. L, to mark--more at sign] (bef. 12c) 1 dial Brit: to make the sign of the cross on (oneself) 2. dial Brit: bless Merriam-Webster English vocab. Английский словарь Merriam Webster. 2012