Synonyms and related words :
acute, afflictive, aggravating, agonizing, annoying, atrocious, biting, bothering, bothersome, chafing, consuming, cramping, cruel, desolating, disquieting, distressful, distressing, disturbing, exasperating, excruciating, fretting, galling, gnawing, grave, griping, harassing, hard, harrowing, harsh, heartbreaking, heartrending, heartsickening, heartwounding, hurtful, hurting, importunate, importune, irking, irksome, irritating, painful, paroxysmal, pesky, pestering, pestiferous, pestilent, pestilential, piercing, plaguesome, plaguey, plaguing, poignant, provoking, pungent, racking, rending, severe, sharp, shooting, spasmatic, spasmic, spasmodic, stabbing, stinging, tearing, teasing, tiresome, torturing, torturous, troublesome, troubling, upsetting, vexatious, vexing, wearisome, worrisome, worrying