TOOTSIE Meaning of TOOTSIE in English tootsie 1 /toot"see/ , n. Slang.1. a sweetheart; darling. 2. a prostitute. [ 1900-05; of uncert. orig. ]tootsie 2 /toot"see/ , n. Slang.tootsy. Random House Webster's Unabridged English dictionary. Полный английский словарь Вебстер - Random House . 2012